DNA Quiz - 11. One ATP is required for the addition of each...

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BIOCHEMISTRY 300: ROSS MACGILLIVRAY DNA Quiz What is this molecule and from which precursors do the nine ring atoms come? Mark the following either True (T) or False (F): 1. DNA is stable at high pH 2. Assuming the size of the average human gene is 10,000 base pairs and the size of the human genome is 3 x 10 9 , we have approximately 300,000 genes. 3. A G:C base pair is more stable than an A:T base pair. 4. DNA is made up of a sugar-phosphate polymer containing nitrogenous bases. 5. Some viruses can reverse transcribe RNA to DNA. 6. Meselson and Stahl demonstrated that DNA replication was nonconservative 7. During replication, DNA is synthesized in a 5' to 3' direction. 8. During transcription, the template DNA strand is read in a 5' to 3' direction. 9. During transcription, RNA is synthesized in a 5' to 3' direction. 10. Purines are synthesized independently and then added to PRPP
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Unformatted text preview: 11. One ATP is required for the addition of each nucleotide by DNA polymerase Short Answers 1. Discuss the differences between the structure of RNA and DNA. 2. Why is guanine oxidation harmful? 3. What are genes, genomes and the genetic code? 4. Draw one cycle of the polymerase chain reaction. 5. Briefly discuss (in 3-4 sentences each) three uses of the polymerase chain reaction. 6. What are the features of a eukaryotic gene and why are they important? 7. Draw the life cycle of the AIDS/HIV virus. Name two potential targets for anti-viral drugs and explain why they are attractive targets. 8. Explain why methotrexate can be used as an anti-cancer drug. 9. Draw the Central Dogma as conceived originally by Francis Crick. What new advance has changed Cricks original Central Dogma scheme? 10. Discuss the similarities and differences between DNA Topoisomerase I and II...
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DNA Quiz - 11. One ATP is required for the addition of each...

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