{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

ho4 - o> 2 o> 3 o favored by good leaving group strong...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
1. What is the maximum number of stereoisomers in the following compound? CH 3 CHOHCHOHCHOHCH 2 OH CHEM140A Handout #4 TA: Winnie Chan Section: Friday, 12:00pm-12:50pm WLH 2112 [email protected] OH: Fridays 1:00pm-1:50pm @ Cafe Roma 2. Chiral or Achiral? Bond Strength of Haloalkanes: C-F 110 kcal/mol C-Cl 85 kcal/mol C-Br 70 kcal/mol C-I 57 kcal/mol You don’t need to memorize the bond length or bond strength, but understand why this is Notes: S N 2 nucleophilic displacement reaction R-X order of reactivity: 1
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: o > 2 o > 3 o favored by: good leaving group strong, basic nucleophile lack of steric hindrance polar aprotic solvents mechanistically: single step - 1 transition state backside displacement inversion of stereochemistry Cl Cl H H cis-1,3-dichlorocyclopentane?-Good leaving groups are weak bases. Weak bases spread out charge. I > Br > Cl >>F-Strong nucleophiles are strongly basic, highly localized charge and not sterically hindered...
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online