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Unformatted text preview: Here’s generally a good rule: Ask yourself these questions: 1. Is the nucleophile a strong base? 2. Is the nucleophile sterically hindered? 3. Is the substrate sterically hindered? (tertiary, secondary, primary branched) *if you have at least 2 “yes”s to the questions, elimination. If not, substitution. 5. Draw a reasonable mechanism for the reaction below. Br > OCH 2 CH 3 +HBr CH 3 CH 2 OH 6. Draw all of the isomers, including stereoisomers of C 5 H 8 Cl 2 which contain a cyclopentane ring. Label any compounds whih are meso stereoisomers and label pairs of enantiomers. 7. Draw reasonable mechanism for the transformation below. Be sure to account for stereochemical outcome of the reaction. OH OSO 2 CH 3 H Base Polar aprotic solvent > O CH 3 H...
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- Spring '07
- pH, Conformational isomerism, Winnie Chan, E2 E2 E2