320Fall09Lecture13 - BIO 320 Cell Biology, Fall 09 Dr....

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
BIO 320 Cell Biology, Fall ‘09 Dr. Thomas Bushart Lecture 13
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Topics Endoplasmic reticulum Vesicle trafficking basics ER to Golgi
Background image of page 2
GPI anchoring Glycosylphosphatidylinositol, lipid raft assoc.? Set up for release from cells Figure 12-56 Molecular Biology of the Cell (© Garland Science 2008)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Membrane growth New lipids are directly synthesized on the cytosolic leaflet of the ER Growth step Figure 12-57 Molecular Biology of the Cell (© Garland Science 2008)
Background image of page 4
Growth problem FAs only gets inserted on cytosolic side Membranes cannot grow if lipids confined to one leaflet Transporters (scramblases and flippases) flip lipids Figure 12-58 Molecular Biology of the Cell (© Garland Science 2008)
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Lipid delivery Phospholipid exchange proteins
Background image of page 6
Organelle inheritance ER, mitochondria, plastids, and peroxisomes are no longer self-assembling structures Components needed to make the organelle require the organelle! An example of epigenetic information At least one distinct protein is required to already be present in the membrane and so must be passed on to offspring What is one candidate? Mito and plastids also contain extra-genomic DNA These types of organelles must grow and divide when the whole cells does
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Translocator proteins Why do these depictions include a slit down the side?
Background image of page 8
Secretory/endocytic pathways ER is connected via “transport packages” to a variety of membrane systems
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/25/2010 for the course BIO 51055 taught by Professor Bushart during the Fall '09 term at University of Texas at Austin.

Page1 / 31

320Fall09Lecture13 - BIO 320 Cell Biology, Fall 09 Dr....

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online