{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

320Fall09Lecture13 - BIO 320 Cell Biology Fall 09 Dr Thomas...

Info icon This preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
BIO 320 Cell Biology, Fall ‘09 Dr. Thomas Bushart Lecture 13
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Topics Endoplasmic reticulum Vesicle trafficking basics ER to Golgi
Image of page 2
GPI anchoring Glycosylphosphatidylinositol, lipid raft assoc.? Set up for release from cells Figure 12-56 Molecular Biology of the Cell (© Garland Science 2008)
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Membrane growth New lipids are directly synthesized on the cytosolic leaflet of the ER Growth step Figure 12-57 Molecular Biology of the Cell (© Garland Science 2008)
Image of page 4
Growth problem FAs only gets inserted on cytosolic side Membranes cannot grow if lipids confined to one leaflet Transporters (scramblases and flippases) flip lipids Figure 12-58 Molecular Biology of the Cell (© Garland Science 2008)
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Lipid delivery Phospholipid exchange proteins
Image of page 6
Organelle inheritance ER, mitochondria, plastids, and peroxisomes are no longer self-assembling structures Components needed to make the organelle require the organelle! An example of epigenetic information At least one distinct protein is required to already be present in the membrane and so must be passed on to offspring What is one candidate? Mito and plastids also contain extra-genomic DNA These types of organelles must grow and divide when the whole cells does
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Translocator proteins Why do these depictions include a slit down the side?
Image of page 8
Secretory/endocytic pathways ER is connected via “transport packages” to a variety of membrane systems
Image of page 9

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern