{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

320Fall09Homework7_key - Cell Biology(BIO 320 Fall 2009 Dr...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Cell Biology (BIO 320), Fall 2009, Dr. Bushart Homework set #7 1. What transport activities in the cell would be negatively impacted by a lack of H + - ATPases? There are numerous ones, but try to come up with at least four (more is better!). Explain how proton transport is important for each example. Some transport we’ve looked at utilize pH as a means to modulate cargo binding by transport receptors. This is the case for at least three different receptors: the KDEL receptor, the M6P receptor, and even the transferrin receptor. Protons also have roles in active transmembrane transport, being used as a concentration gradient. There are a number of different possibilities, but one recent one is the H+-glutamate exchanger in synaptic vesicles. The charge difference partly from the proton gradient was also used in mitochondria to drive the uptake of the signal peptide in mitochondrial transport. pH and acidification of compartments also play roles in protein processing during transport. pH may allow transported enzymes to become active (as in the case of acid hydrolases) or contribute to their aggregation (as in the concentration of secreted proteins during regulated exocytosis).
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern