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BIOL 595-10-22-09 (F 2009)

BIOL 595-10-22-09 (F 2009) - Models of neural Patterning by...

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BIOL 595 10-20-09 Vertebrate 3: Neural Patterning and Specification
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Specification of Neuroectodermal Domain
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Ne ural Tube  Fo rm atio n in C hic k
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Scheme of Neural Tube Formation Neural tube formation results from the formation and fusion of neural folds
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Neuroectodermal (Neural) Tissues 1) Forebrain, midbrain and hindbrain 2) Hindbrain subdivides into 8 rhombomeres 3) Spinal cord 4) Central nervous system (CNS)
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What patterns the development of different neural tissues along the anterior-posterior axis?
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Neural plate can be patterned by signals from mesoderm
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Two-signal Model 1) One signal from the mesoderm first induces anterior tissue throughout the corresponding ectoderm 2) Second graded signal from the mesoderm then specifies more posterior regions
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Neural Patterning by qualitatively different inducers are localized in the mesoderm
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Unformatted text preview: Models of neural Patterning by Induction Dive rs e C e ll Type s in the Ne rvo us S ys te m Diffe re nt Ne uro na l C e ll Type s Diffe re nt s uppo rting c e lls (g lia l c e lls ) Nervous System Ne urite s 1) Lo ng e xte ns io ns fro m the c e ll b o dy 2) Ma y c o nduc t ne rve im puls e s e ithe r to wa rd the c e ll b o dy o r a wa y fro m it The Nervous System Dendrites carry impulses toward the cell body Axons carry impulses away from the cell body Afferent (neurites) - carry impulses toward the cell body Efferent (neurites) - carry impulses away the cell body Impulses of Neurites How are neuronal precursors (neuroblasts) specified during neurogenesis? Invertebrate Neural Development Neural versus Non-neural Neuroblast of Sensory Organ...
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