Lim Development Lecture (IV) 11-10-09 F2009

Lim Development Lecture (IV) 11-10-09 F2009 - BIOL 595...

Info iconThis preview shows pages 1–18. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: BIOL 595 11-10-09 Limb Development (IV) Dorsal – Ventral Axis Ectoderm Controls D/V Patten in the Developing Limb Bud Figure 9.14 (Page 350) Proximal – Distal Identity Figure 9.16 (Page 352) Figure 9.17 (Page 353) Change in Expression of Hoxd Genes Following a Polarizing Region Graft Figure 9.18 (Page 353) Region of Hox Gene Expression in the Mouse Forelimb Forelimb versus Hindlimb Figure 9.15 (Page 352) Chick Proximal Leg Bud Cells Grated to a Distal Position in a Wing Bud Acquire Distal Postional Values Leg Bud Cells Grafted to Wing Bud of Chick Tbx5 and Tbx4 regulate Limb Outgrowth Conclusion of Figure 1 1) Viral injection causes limb development to be arrested 2) Disrupted and splitting of AER (figure 1a-d) 3) Common phenotypes- Hypoplasia or disappearance of zeugopod elements (radius in wing, figure 1f and fibula in the leg, figure 1i and j- Absence of anterior digits (digit II in the wing, figure 1f and digits I and II in the leg (figure 1l) Feedback regulatory loops between Tbx5/4 and the FGF, WNT and BMP Conclusions of Figure 2g-j...
View Full Document

This note was uploaded on 01/27/2010 for the course BIOL 595 taught by Professor Staff during the Spring '08 term at Purdue University.

Page1 / 26

Lim Development Lecture (IV) 11-10-09 F2009 - BIOL 595...

This preview shows document pages 1 - 18. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online