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Unformatted text preview: Bio 401 W2010 Crowe Name:_______________________ Section: ___________ 1 PRACTICE MIDTERM QUESTIONS Multiple Choice (Circle the letter corresponding to the correct answer) ___ 1. (1 pt.). Which of the following activities would you expect to be influenced by histone acetylation? COMPREHENSION A. Transcription B. DNA repair C. DNA replication D. All of the above ___2. (1 pt.). What is the primary purpose of a chromatin immunoprecipitation assay (ChIP)? COMPREHENSION A. To identify methylated DNA in promoter regions of genes B. To identify proteins that interact with a specific DNA sequence in a cell C. To detect protein/protein interactions D. To measure the ability of a transcription factor to activate transcription E. To obtain the 3 dimensional structure of a protein ___3. (1 pt.). Which of the following questions could be best answered with a reporter gene assay? APPLICATION A. Is the myosin gene expressed in mouse brain? B. Can the Pax6 transcription factor activate expression of the myosin gene? C. Does the 5 kb upstream of the myosin gene contain an enhancer responsible for activating myosin gene expression in muscle by embryonic day 12 (E12)? D. Is the myosin gene localized to the nuclear periphery?...
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- Winter '10
- cell biology