BIS101-Mid1 - 09

BIS101-Mid1 - 09 - Chan Midterm 1 Answer Key, Winter 2009...

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Chan Midterm 1 Answer Key, Winter 2009 1. (11pts) You have identified 6 Drosophila mutants that are defective for flying; you designate your mutants fly1-fly6. You decide to perform complementation tests. You complete the complementation tests for fly1, fly2 and fly3 and obtain the following results: Fly1 fly2 fly3 fly4 fly5 fly6 fly1 - + + + + - fly2 + - - + - + fly3 + - - + - + fly4 + + + - + + fly5 + - - + - + fly6 - + + + + - a) Predict the outcome of complementation test with fly4, fly5 and fly6 by filling in completely the table above (3pts). b) How many different complementation groups are represented by fly1-fly6? Three complementation groups c) Which mutants fall into the same complementation group? - fly1,6 - fly2,3,5 - fly4 D) You are particularly interested in fly4. Interestingly you find that when the flies are grown at 15 0 C they can fly but at 20 0 C they can not fly. What type of allele is fly4? 1 word please. (2pts) Conditional (or temperature sensitive)
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2. (16pts) In mice, a recessive mutation in gene T results in tail-less animals and a second unlinked recessive mutation in gene F results in fat animals. Indicate the genotypes of the parents of the following crosses, a-d, in the space below. Phenotype of Progeny : Phenotype of Parents Tail Tail tail less tail less Slim fat Slim fat (a) Tail, Slim x tail-less, fat 24 0 25 0 (b) Tail, Slim x tail-less, Slim 30 10 29 11 (c) Tail, Slim x Tail, fat 15 14 4 5 (d) Tail, fat x tail-less, Slim 8 9 9 9 a) (4pts) TtFF x ttff b) (4pts) TtFf x ttFf c) (4pts) TtFf x Ttff d) (4pts) Ttff x ttFf
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3. (10pts) In birds, assume blue feather color is dominant to yellow feather color and all animals are true breeding. A yellow-feathered male is crossed to a blue-feathered female. and the all of the male offspring have blue feathers while all of the female offspring have yellow feathers. However, when the reciprocal cross is performed, blue-feathered male crossed to a yellow feathered female all of the offspring is blue. Please explain this result and indicate the genotypes of the parents and offspring from these crosses. (Hint: females are the heterogametic sex and have ZW sex chromosomes and males are the homogametic sex in birds with ZZ chromosomes). a.
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BIS101-Mid1 - 09 - Chan Midterm 1 Answer Key, Winter 2009...

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