MT1_09WhiteKey

MT1_09WhiteKey - Name White Key Last, First BIS102-02,...

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Name White Key BIS102-02, Spring '09, Page 1 of 7 Last, First C. S. Gasser BioSci 102-02 Apr. 21, 2009, First Midterm Instructions: There are seven pages in this exam including the cover sheet, please count them before you start to make sure all are present. Write your name on each page of the exam. Write your answers in the space provided below each question. If you need more space use the back of the page and indicate clearly that you have continued your answer on the back. Do not use additional paper. For calculation problems a clear line of calculations leading to your final answer must be shown to obtain full credit. Use the following pK a values for the exam. Amino Acid α -NH 2 α -COOH R-group log 1.0 = 0.00 Ala, Gly, Ile, Leu, Val 9.7 2.3 log 1.5 = 0.18 Asn, Gln 9.0 2.1 log 2.0 = 0.30 Met, Ser, Trp 9.3 2.3 log 2.5 = 0.40 Phe 9.1 1.8 log 3.0 = 0.48 Pro 10.6 2.0 log 3.5 = 0.54 Thr 10.4 2.6 log 4.0 = 0.60 Asp 9.8 2.1 3.9 log 4.5 = 0.65 Glu 9.7 2.2 4.2 log 5.0 = 0.70 His 9.2 1.8 6.0 log 5.5 = 0.74 Cys 10.8 1.8 8.3 log 6.0 = 0.78 Tyr, Lys 9.1 2.2 10.0 log 6.5 = 0.81 Arg 9.0 2.2 12.5 log 7.0 = 0.85 log 7.5 = 0.88 Question Value Score log 8.0 = 0.90 1 24 log 8.5 = 0.93 2 12 log 9.0 = 0.95 3 16 log 9.5 = 0.98 4 30 log 10.0 = 1.00 5 12 6 23 R = 8.3 X 10 -3 kJ/°K•mol 7 18 25°C = 298K 8 15 Total 150
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Name White Key BIS102-02, Spring '09, Page 2 of 7 Last, First C. S. Gasser 1) (24) Write the one and three letter codes for all of the amino acids whose side chains (R- groups) fit into the following categories. a) (6) The neutral form can act as a proton donor. Asp, D; Glu, E; Tyr, Y; Cys, C b) (6) Contains at least one nitrogen atom. Asn, N; Gln, Q; Trp, W; His, H; Lys, K; Arg, R c) (6) Contains an alcohol group. Ser, S; Thr, T; Tyr, Y d) (6) Could form a salt bridge with the side chain of aspartate at pH 6.0.
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This note was uploaded on 01/29/2010 for the course BIS 102 taught by Professor Hilt during the Spring '08 term at UC Davis.

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MT1_09WhiteKey - Name White Key Last, First BIS102-02,...

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