vsc 433 exam 4 & 5 study guide

vsc 433 exam 4 & 5 study guide - VSC (MIC) 433 and 533,...

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VSC (MIC) 433 and 533, Medical and Molecular Viroloy, Fall 2005 Study Guide Exam 4 + 5 : Length: 1011 words (2.9 double-spaced pages) Rating: Red (FREE) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - VSC (MIC) 433 and 533, Medical and Molecular Viroloy, Fall 2005 Study Guide Exam 4 + 5 UA University of Arizona 64 If you designed an inhibitor of RT (the reverse transcriptase part of RT), would you expect it to be toxic to a cell? Why or why not? 65 Describe 2 accessory genes found in Lentiviruses (but not in RNA tumor viruses) and describe their function. 66 What features distinguish the RNA tumor virus group (“Oncornviruses”) from the Lentivirus group? 67 Most Oncornavirinae do not kill the cell. Provide an explanation as to why this is advantageous for survival of the virus. 68 Name three families of viruses (and give an example of one specific virus of each family) that carry genes that cause cancer. 69 Why is “viral load” relevant to AIDS? 70 What are the differences in the HIV epidemics in Africa versus the USA? How are these differences explained? 71 What is the difference between v-onc, c-onc, and proto-onc? In other words, what is Temin’s Proto- oncogene theory? 72 Oncornavirinae provided the first solid evidence that a gene can cause cancer. What is this evidence? 73 Oncornavirinae can induce cancers or tumors by mechanisms which have a short incubation period or a very long latent period. Contrast the mechanisms involved. 74 What is meant by a “defective transducing (DT) retrovirus”? Explain a possible origin for these
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This note was uploaded on 01/30/2010 for the course VSC 433 taught by Professor Dr.jimcollins during the Fall '08 term at Arizona.

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vsc 433 exam 4 & 5 study guide - VSC (MIC) 433 and 533,...

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