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BISC 330 Spring 2010 Lecture 2

BISC 330 Spring 2010 Lecture 2 - BISC330L:Biochemistry...

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BISC 330L:  Biochemistry Spring Semester 2010 USC Lecture:  Wednesday, 13 Jan 2010 1. Finish Monday’s material.  2.Continue Chapter 1 material…
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Chapter 1:  Biochemistry An Evolving Science Diverse, yet similar… Structure/function analysis of DNA General chemistry review Properties of water Acid-base reactions in biochemical  processes
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Review of Chemistry Covalent Bonds  sharing electrons  stability is the key  polar v. nonpolar molecules  water is polar  C,H are nonpolar Non-covalent bonds  opposites attract!  Ionic bonds:  Na+  Cl-   Hydrogen bonds: weak  Hydrophobic interaction  van der Waals force
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Covalent bonds require sharing  of electrons
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Review of Chemistry Covalent Bonds  sharing electrons  stability is the key  polar v. nonpolar molecules  water is polar  C,H are nonpolar Non-covalent bonds  opposites attract!  Ionic bonds:  Na+  Cl-   Hydrogen bonds: weak  Hydrophobic interaction  van der Waals force
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Common noncovalent H-bond in DNA,  RNA and proteins δ - δ - δ + = C δ +
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Hydrogen Bonds Electrostatic interactions Weaker than covalent bonds Energies range from 4-20kJ/mol Longer than covalent bonds Usually exist on a straight line
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Even nonpolar groups can weakly attract by  induced dipole (van der Waals) interaction
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