BISC 330 Spring 2010 Syllabus

BISC 330 Spring 2010 Syllabus - BISC 330 BIOCHEMISTRY -...

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BISC 330 BIOCHEMISTRY - SPRING 2010 Lecture Syllabus Topics : Biochemical bonds and reactions. Interactions with water molecules. Structure/function of DNA, RNA, proteins, lipids and carbohydrates. Enzyme kinetics and mechanisms. Enzyme cofactors and vitamins. Enzyme regulatory strategies. Cell structure, membranes and organelles. Protein biosynthesis and targeting to membranes and organelles. Glucose and O 2 production by photosynthesis in plant chloroplasts. Glucose oxidation and ATP production: glycolysis, citric acid cycle & oxidative phosphorylation. Ribose biosynthesis from glucose by pentose phosphate pathway. Professors: Dr. John Petruska, Tel: (213) 740-5189, Email: petruska@usc.edu Office: MCB (RRI) 119B, Office Hours: RRI 121 Tues/Thurs 11am - 1pm Dr. Steven Goodman, Tel: (213) 740-3867, Email: sgoodman@usc.edu Office: DEN 4108, Office Hours: TBA Dr. Angel P. Tabancay, Jr., Tel: (213) 740-8352, Email: tabancay@usc.edu Office: ZHS 256, Office Hours: ZHS 256 Monday 3-5pm Text Lecturer, Date Subject Chapter AT, Jan 11 Biochemical bonds and reactions 1.1-1.3 13 Water, pH and acid/base equilibria 1.3 15 1.4 18 No Lecture - Martin Luther King Day 20 Amino acid structures & properties 2.1 22 Primary structure of proteins 2.2 25 Secondary structure 2.3 27 2.4-2.6 29 Protein purification methods 3.1 Feb 1 3.2 AT, Feb 2 MIDTERM EXAM #1 4:00-5:30pm TBA 175 points 1
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AT, Feb 3 Protein structure determination 3.3-3.6 5 4.1,4.2 8 4.3-4.6 JP, Feb 10 Intro. to thermodynamics & kinetics 8.1-8.3 12 Enzyme kinetics: M-M model 8.4 15 No Lecture - Presidents Day 17 Enzyme kinetics with inhibitors 8.5 19 Enzyme catalytic strategies 9.1-9.4 22 Enzyme regulatory strategies 10.1--10.4 24 Carbohydrate structures 11.1-11.4 26 12.1-12.5 Mar 1 15.1-15.4 JP, Mar 2 MIDTERM EXAM #2 4:00-5:30pm TBA 175 points Mar 3 Cell structure & organelles: nucleus, mitochondria & chloroplasts 12.6 18.1,19.1 5 Cell membranes & vesicles, RER, Golgi, lysosomes, micro-tubules & -filaments. 11.3, 30.6 34.2, 34.3 8 Protein targeting to membranes 30.5, 30.6 10 Photosynthesis: Chlorophyll absorbs light used to split covalent O-H bonds in H2O 19.1,19.2 12 PS I,II & Cyt bf action: pump H+, store H- 19.3 15-19 NO LECTURES - SPRING BREAK 22 ATP synthesis using H+ current 19.4 24 Glucose synth. using ATP & H- in NADPH 20.1,20.2 26 Ribose synthesis by Pentose Phos. Pway 20.3 29 Ribose synthesis by Pentose Phos. Pway 20.3 JP, Mar 30 MIDTERM EXAM #3 4:00-5:30pm TBA 175 points SG, Mar. 31 Glycolysis: Glucose -> 2 Pyruvate 16 Apr 2 Citric Acid Cycle: Entry of pyruvate 17 5 17 7 17 9 CA Cycle: Net reaction and energetics 17 12
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This note was uploaded on 01/30/2010 for the course BISC 330 taught by Professor Petruska during the Spring '08 term at USC.

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BISC 330 Spring 2010 Syllabus - BISC 330 BIOCHEMISTRY -...

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