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Unformatted text preview: Chem114A, 2006 Practice Problem Set 1. Describe what is the fluid mosaic model. According to the fluid mosaic model, integral membrane proteins are free to diffuse laterally within a lipid bilayer due to its lateral fluidity. The movement of membrane proteins may be limited by their interactions with other membrane proteins or with cytoskeletal proteins underlying the membrane. 2. Is fluid mosaic model temperature dependent? Yes. Fusion of two membranes could not occur at low temperature because the fluidity of the membranes is too low to allow the free diffusion of lipids and proteins. At a higher temperature, the membranes are more fluid, making the lateral movement of lipids and proteins possible. 3. Explain why an erythrocyte membrane that synthesizes too little spectrin is a sphere rather than a biconcave disk. In normal erythrocytes, the cross-linking of spectrin and other membrane proteins creates a submembrane network of proteins, somewhat akin to a geodesic dome, that gives the cells a biconcave...
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- Fall '06