3.drugs.or.poisons

3.drugs.or.poisons - Natural Substances Drugs or Poisons?...

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Unformatted text preview: Natural Substances Drugs or Poisons? Natural Bioactive Compounds Magic Bullets? Ergot Alkaloids Penicillins Opioids Tropane Alkaloids Summary and Conclusions I. Natural Bioactive Compounds Chemicals found in nature that cause biochemical or physiological actions in organisms. Phytotoxins Bioactive chemicals from plants. Mycotoxins Bioactive chemicals from molds and fungi. Both classes represent the two main sources of drugs on the market today. Common Natural Drug Types Analgesics cause temporary pain relief (aspirin, etc). Narcotic analgesics produce a sleep-like painless state (morphine, codeine, etc). Anesthetics block pain nerves (cocaine, etc). Stimulants stimulate activity (caffeine, nicotine, etc). Sedatives produce general sedation (alcohol, etc.). Antimicrobials cure infectious diseases II. Mycotoxin Example Ergot Alkaloids Produced by molds that infest stored grains (rye). Noted as far back as 600 BC by the Assyrians. Caused gangrenous and convulsive ergotism (St. Anthonys Fire). Symptoms included convulsions, hallucinations, gangrene and spontaneous abortions....
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This note was uploaded on 02/01/2010 for the course ETX etx10 taught by Professor Rontjeerderma during the Fall '09 term at UC Davis.

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3.drugs.or.poisons - Natural Substances Drugs or Poisons?...

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