6.moon.rocks.exposure.potency

6.moon.rocks.exposure.potency - Moon Rocks Exposure Versus...

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Moon Rocks – Exposure Versus Potency Potency May be Measured for Many Effects Margin of Safety Threshold Dose – More Important than Potency? Reference Dose Response to Essential Chemicals Is Knowing Potency Enough? Summary and Conclusions
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. Potency May be Measured for Many Effects
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II. Margin of Safety
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Margin of Safety – What it Means Necessary to determine for drugs. Commonly measured via the therapeutic index. Large TI value = over-the-counter drugs. Moderate TI value = prescription drugs. Small TI values = physician-administered drugs.
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Therapeutic Index Calculation can be liberal or conservative. Liberal – TI = TD50 / ED50 Conservative – TI = TD1 / ED99 The conservative approach is usually most protective.
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Threshold Dose – More Important than Poten
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Threshold Versus Non-Threshold Threshold chemicals require a certain amount before a toxic effect can occur. Non-threshold chemicals in theory can cause
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This note was uploaded on 02/01/2010 for the course ETX etx10 taught by Professor Rontjeerderma during the Fall '09 term at UC Davis.

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6.moon.rocks.exposure.potency - Moon Rocks Exposure Versus...

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