MECH466-Lecture-20 - MECH 466 Microelectromechanical...

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1 MECH 466 Microelectromechanical Systems University of Victoria Dept. of Mechanical Engineering Lecture 20: Microfluidic MEMS July 19th, 2007 Mech 466, N. Dechev, UVic 2 Introduction to Microfluidics Concept of ‘Lab on a Chip’ Basic Fluid Mechanics Concepts Reynolds Number Basic Equations Applications of Microfluidics Overview Mech 466, N. Dechev, UVic
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3 What is Microfluidics? Microfluidics is the science and technology involved in liquid transfer, separation, mixing and analysis, for ‘micro-volumes’ of fluids. One of the main thrusts of microfluidic research is the attempt to create a ‘lab on a chip’ to allow for the chemical analysis of small samples of fluids. Mech 466, N. Dechev, UVic [Image from Chang Liu] 4 The motivation for using a microfluidic system is analogous to the argument for using integrated circuits to replace the discrete component circuits. Advantages: - Miniaturization - Integration - Automation Limits - some fluid reactions require a large volume and quantity Mech 466, N. Dechev, UVic Advantages of a Microfluidic System Portability Low Costs Simplicity of operation
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5 Mech 466, N. Dechev, UVic Example of Rapid Bio DNA Detection Chip [Image from Chang Liu] 6 Mech 466, N. Dechev, UVic Example: Lab-on-a-CD The objective is to use the spinning disk (at 7,000+ RPM) to generate the angular and radial acceleration to ‘drive’ the fluid through the microfluidic channels. Additionally, the laser head (or other optical scanner) is modified to detect color, or other properties of the reacting fluids. The electronics package provides the test results from processing. For more information: Search google with “Lab on a CD”, or “Lab on a Chip” BioDisk Player [IMTEK] Lab on a CD [NASA Ames Research Center ]
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! ) Dynamic Viscosity (μ), (also simply called Viscosity) Eg: Viscosity of water: 0.01002 Poise, or 1.002 cP (centipoise) Kinematic Viscosity ( " ) 7 Mech 466, N. Dechev, UVic Basic Fluid Mechanics Concepts (Velocity) (direction) Boundary/Surface 8 Shear deformation of a fluid: Mech 466, N. Dechev, UVic Basic Fluid Mechanics Concepts ! u
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MECH466-Lecture-20 - MECH 466 Microelectromechanical...

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