Extended Homework Problems for HW5

Extended Homework Problems for HW5 - Extended Homework...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Extended Homework Problems for HW #5 (from chapter 6) 4. Protection of an Enzyme against Denaturation by Heat When enzyme solutions are heated, there is a progressive loss of catalytic activity over time due to denaturation of the enzyme. A solution of the enzyme hexokinase incubated at 45 °C lost 50% of its activity in 12 min, but when incubated at 45 °C in the presence of a very large concentration of one of its substrates, it lost only 3% of its activity in 12 min. Suggest why thermal denaturation of hexokinase was retarded in the presence of one of its substrates. 7. Effect of Enzymes on Reactions Which of the listed effects would be brought about by any enzyme catalyzing the following simple reaction (a) decreased K’ eq ; (b) increased k 1 ; (c) increased K’ eq ; (d) increased Δ G ; (e) decreased Δ G ; (f) more negative Δ G ′°; (g) increased k 2 . 8. Relation between Reaction Velocity and Substrate Concentration: Michaelis-Menten Equation (a) At what substrate concentration would an enzyme with a
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/02/2010 for the course BIOCHEM Biochem440 taught by Professor Dr.klevit during the Winter '09 term at University of Washington.

Page1 / 2

Extended Homework Problems for HW5 - Extended Homework...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online