Unformatted text preview: D ? 13) Do graphs A, B and C resemble the binding curve of Myoglobin or Hemoglobin? Why? 14) Draw cooperative binding curves (where N>n>1, and n a =n b =n c same Hill Coeffcient) for the same K D s as above, label curves with lower case letters respectively.( e.g.(K D(A) = K D(a) ) 15) What type of curve is it? 16) Write an equation for Ɵ(O 2 ) as a function of pO 2 . 17) What is the value of Ɵ at p 50 ? 18) Is the oxygen affinity of Hemoglobin in the lungs high or low? Why? 19) What about the oxygen affinity of Hemoglobin in tissues? 20) Why does hemoglobin have different affinities for O 2 in lungs and tissue? 21) If you could synthesize a drug that would enhance your O 2 release in the tissues what would its function be? 1 0.5 1.0 1.5 2.0 2.5 0.5 3.0 3.5 (μM)...
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- Winter '09
- Proteins, Hemoglobin, binding affinity, Ligand binding affinity, independent binding curve