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Unformatted text preview: BIO 188 November 6, 2009 BIO 188 November 6, 2009 Nernst simulator link You are responsible for everything in Wed outline even though we wont go through everything in lecture Details of chemical synapse will be on Final Exam, not Exam 3 Today: 1. a few questions about membrane potential 2. generation of action potential 3. propagation of action potential 4. time for questions? Clicker: 5. Polrized 6. All of the above 7. Hyperbolized is more negative charge Neurons and muscle cells are excitable! What does that mean? .. Are subject to transient changes in membrane permeability ( Are subject to transient changes in membrane permeability ( Vm) and can fire Vm) and can fire action potentials action potentials What does a cell need in order to be excitable? ... gated ion channels 1. excitable cells have ligand-gated ion channels ligand-gated ion channels to respond to signal from another cell 2. cell membrane needs voltage-gated voltage-gated ion channels ion channels to fire action potentials Neuronal signaling based on r apid changes in Vm Neuronal signaling based on r apid changes in Vm...
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- Spring '08