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Unformatted text preview: PS 111A Winter 2010 Week 1 1. Using a picture, describe and define resistance and capacitance in the context of the SGA lipid bilayer. 2. The SGA membrane could be described as a resistor and capacitor that are: a. In series b. In parallel c. All of the above d. None of the above 3. What happens to R and C as you add/stack more lipid bilayers on top of each other? 4. Describe what is happening in the figure below and how it relates to the SGA bilayer.
s t=0 •
Voltmeter V2 V1 t=1 2 • 5. Calculate the dielectric constant of a typical membrane using lecture notes. 6. You are a physician treating a patient presenting with worsening heart failure. A possible therapy is to prevent intracellular sodium from being actively pumped out of the cardiac myocytes. What could you prescribe to your patient and why? 7. Compare and contrast the Nernst and Goldman Equations. 8. Describe Ohm’s Law in the context of excitable cells. What does it have in common with the Goldman Equation? 9. Assuming resting potential of 100 mV, calculate the available pool of potassium ions in an unmyelinated “c” fiber. Why is it important that only a few ions from the available pool are needed to develop the resting potential? 10. Describe the following figure: 11. Define and describe the graded potential. 12. If you were a graded potential that wanted to defy decay, what kind of axon would you want to be in and why? ...
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This note was uploaded on 02/03/2010 for the course NEUROSCI 101A taught by Professor Scheibell during the Winter '10 term at UCLA.
- Winter '10