Lecture 3 08 - 1 Nervous System 2 Dr Phelps Chapter 13...

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Unformatted text preview: 1 Nervous System 2 Dr. Phelps Chapter 13 Lecture 3 Major concepts: I. Nervous system development forms the basis for adult structures. II. Meninges and ventricles surround the outside and inside of the CNS. III. Cerebral cortex: functional areas. I. Nervous system development forms the basis for adult structures. This short computer-based multimedia presentation is available on the Internet at the class web site: http://www.lsic.ucla.edu/classes/ 1 and 2- Review of neurulation • Ectoderm in the dorsal midline induced by the notochord to thicken - forms the neural plate. • Edges of the neural plate begin to fold toward each other - called the neural folds . • Neural folds meet dorsally forming the neural tube & overlying ectoderm . • Neural plate enlarges dorsally: neural folds meet in the midline to form neural tube and dorsal ectoderm. • Neural tube closes first near middle of the embryo and proceeds rostrally and caudally, reflecting the gradient of nervous system development. Medulla and cervical spinal cord develop first. 3- Cross section of neural tube • Some neural crest cells remain near the neural tube to give rise to sensory afferent neurons. • Neural tube composed of cells that undergo mitosis to form the CNS. • Central cavity enclosed by neural tube called the ventricle- forms the ventricular system. 4 and 5 - Cell division in neural tube • Neural tube cells first generate neurons, then glia. • Neural tube cells have processes attached to both inner (ventricular) and outer surfaces of the neural tube. Their nuclei move back and forth during the cell cycle (G1, Synthesis, G2, Mitosis)....
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Lecture 3 08 - 1 Nervous System 2 Dr Phelps Chapter 13...

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