TriglycerideHydrolysisKey

TriglycerideHydrolysisKey - adenylate cyclase 1. HSL (less...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
a. Kinesiology 200 Lab Computer Lab - Triglyceride Hydrolysis (10 points) KEY Draw the three steps of triglyceride (TG) hydrolysis, including enzyme names. Highlight the enzymes in yellow. triglyceride + HzO ---+ digtyceride + FA TG lipase (or HSL) diglyceride + HzO --+ motloglyceride + FA TG lipase (or HSL) monoglyceride + HzO -, glycerol + FA MG lipase Following TG hydrolysis in the adipose tissue, glycerol is released into the blood. Where does it go from there? liver Following TG hydrolysis in the adipose tissue, where do the fatty acids (FA) go? Mitochondria (in AT or other tissue like heart, muscle, or liver) What are the FA's (from question #3) used for? ATP production via beta oxidation & Krebs cycle (can also be used for TG synthesis in the liver) Draw a representation of the
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: adenylate cyclase 1. HSL (less active HSL-P (active) .--TG--*FA's---+glycerol 2. 4. 6 CAMP r**v PK.A PKA-P (less active (active) or inactive {"-a*.-"^ " "-'-**"'-&*q*,*"--. ... t/n phosphodiesterqse--+ r )) 5'adenylate ,E ottn"gr,ul) ._,*. __*.--a protein phosphatase 6. Fill-in the followino table. Effect on TG Hydrolysis Detailed Mechanism Catecholamines (via cr2 receptor) INC DEC Inhibit adenylate cyclase.--- IcAMP---+ JPKA (active)--- JHSL-P Catecholamines (via B1 receptor) INC / DEC Stimulate adenylate cyclase.--- fcAMP --+ lPKA (active)--- tHSL-P Insulin INC / DEC Mechanism #1 f phosphodiesterase---+ JcAMP --- J PKA (active) -' JHSL-P Mechanism #2 Jprotein phosphatase---) t HSL (not phosphorylated, therefore less active) Exercise INC / DEC J catecholamines (via p1 receptor) J insulin Fasting INC / DEC J insulin Fed INC / DEC f insulin...
View Full Document

Page1 / 2

TriglycerideHydrolysisKey - adenylate cyclase 1. HSL (less...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online