BenzerSPR2008rII

BenzerSPR2008rII - A gene is . Mendel=unit factor...

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A “gene” is …………………………………. Mendel=unit factor Garrod=inborn error of metabolism alkaptonuria Oliver lz, Yanovsky trpA, Lewis Str Benzer=complementation
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Seymour Benzer 1921 – 2007 Used recombination to make a map of a viral gene Used mixed infection to identify the number of genes/complmnttion. Then: behavioral genes circadian genes neurobiology A GIANT who never bored himself by doing the same thing
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A.H. Sturtevant Mendel’s II is based on metaphase I alignment EXCEPTIONS were quickly found! Imprinting and uniparental disomy AB/ab x ab/ab all ab + AB or aB + Ab LINKAGE Linkage means that loci are on the same DNA molecule. If they are far apart crossing over or recombination will mimic Mendel’s II. Sturtevant used flies to make map
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Do not lose the forest for the trees. Recombination maps are always # recombinants/total THAT’s IT! AaBb X aabb
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BenzerSPR2008rII - A gene is . Mendel=unit factor...

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