Txn - Nontemplate strand 5 Template strand 3 s Figure 4-1...

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Unformatted text preview: Nontemplate strand 5' Template strand 3' s! Figure 4-1 0b Molecular Cell Biology, Sixth Edition 0 2008 w. H. Freeman and Company Promoter -30 —20 Upstream -10 Transcription r_. +10 Coding sequence +20 Downstream 3’ Primary RNA transcript +1 (transcription start site) PromoterY CAP site Operator E. coli lac transcription-control regions up 0 (a) ' lac repressor - lactose + glucose . . (low cAMP) No mRNA transcriptlon (b) - + lactose =‘ h— """"" " + glucose (low cAMP) I Low transcription IIIIIIIIII» + lactose (Triggllrizfip) High transcription Figure 7-2 Molecular Cell Biology, Sixth Edition 0 2008 W. H. Freeman and Company [NaCI] —> Total 3 protein é o T Pol II 3. : VI .— 7. .2 a: m T? .2: .5, a a ul-I < VI 2 z Pol III <2"- n. a: a: 10 20 3O 40 50 Fraction number Figure 7-8 Molecular Cell Biology, Sixth Edition © 2008 W. H. Freeman and Company —> OH pg/ml a-amanitin direction of DNA double RNA polymerase transcription, lelix \U‘ ribonucleoside ‘; 3...... ytriphosphates . , . ribonucleoside RNA exut actlve sute triphosphate A 5 channel uptake channel newly synthesized short region of RNA transcript DNA/RNA helix Figure 6-8a Molecular Biology of the Cell 5le (0 Garland Science 2008) ...
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