H3 - ECEN 689 Statistical Computation in Genomic Signal...

ECEN 689 - Statistical Computation in Genomic Signal Processing
Fall 2009
Homework 3
Due on: October 28, at the start of class.
Homework Policy :
• You are expected to write and code in a clean and documented style, and demonstrate
that you understood the problem and its solution.
• You can discuss the problems with your colleagues if you wish but each student must code
their own solutions separately.
• Late homework cannot be accepted, unless there is a documented valid reason.
• Please e-mail me a PDF with your answers and code in one PDF.
Problems:
1. Suppose that for a given probe set, all the PM values are constant and euqal to α
P
, whereas
all MM values are also constant and equal to α
M
. If α
P
≤ α
M
then clearly the probe set
will be called “absent” (A). If α
P
> α
M
, explain in detail what happens.
Hint: You may find useful experimenting with the R function wilcox.test() , using the
parameter alternative="greater" .