10-16-09_glycolysisTCA - Announcements Online quiz 5 due by...

Info iconThis preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon
Announcements Online quiz 5 due by noon Tuesday (20 October 2009)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Metabolism definitions Metabolism: Collection of biochemical pathways in a cell Anabolic pathways: Synthesis of more complex compounds from simpler compounds Catabolic pathways: Disassembly of complex compounds to form simpler compounds Metabolic intermediates (metabolites): Compounds formed between the beginning and end of a metabolic pathway. Depending on cell’s needs and conditions, metabolites of one pathway may be used as metabolites or regulators for another pathway. CH 3 CH 2 OH + NAD+ ↔ CH 3 CH=O + NADH + H+ (in liver) http://www.elmhurst.edu/~chm/vchembook/642alcoholmet.html
Background image of page 2
General anabolic and catabolic pathways
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
A small number of precursors and energy through ATP hydrolysis give rise to macromolecules
Background image of page 4
Oxidation-reduction (redox) reactions Oxidation – loss of 1+ electrons, CO2 + H20 ↔ HCO3- + H+ Reduction – gain of 1+ electrons, CO2 + H20 ↔ HCO3- + H+ The oxidized substance is called the reducing agent because it donates electrons The reduced substance is called the oxidizing agent because it gains electrons mmm…partially hydrogenated, fully reduced vegetable oil in chips
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
How do we make the energy for all this transport and other processes? C ATP
Background image of page 6
Locations of different energy producing processes in the cell
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Feel the rush…oxidation of glucose provides lots of energy to cells C 6 H 12 O 6 + 6 O 2 ↔ 6 CO 2 + 6 H 2 O (aerobic) ΔG°’ for this reaction is -686 kcal/mol ! Sugar is disassembled in many small steps to take advantage of the huge free energy difference Energetically favorable steps in the reaction can be coupled with unfavorable reactions in this and other metabolic pathways The more H atoms that can be stripped from a "fuel" molecule, the more ATP can be made Fats > carbohydrates > proteins for chemical energy storage
Background image of page 8
History of glycolysis 1897: Hans & Eduard Buchner, attempting to manufacture cell-free extracts of yeast for possible therapeutic use, added sucrose as a preservative, and discovered that the sucrose was fermentedinto alcohol by the yeast juice!!! The Buchners demonstrated for the 1st time that fermentation could take place outside living cells.
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Studies of muscle extracts then showed that many of the reactions of lactic acid fermentation were the same as alcohol fermentation. This discovery revealed an underlying
Background image of page 10
Image of page 11
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/09/2010 for the course BIOL 230 taught by Professor Bartlett,e during the Fall '08 term at Purdue University-West Lafayette.

Page1 / 32

10-16-09_glycolysisTCA - Announcements Online quiz 5 due by...

This preview shows document pages 1 - 11. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online