NHFinalABCkey'05

NHFinalABCkey'05 - Biological Sciences 101 Dr Neil Hunter...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Biological Sciences 101 Name_________________________ Dr Neil Hunter Fall Quarter 2005 ID___________________________ FORM A,B,C key ( 1 pt) Final Exam This exam contains eight questions worth a total of 200 points . If you do not understand a question don’t hesitate to ask for clarification. Please show all your work to get full credit. Good luck! Authorization for public distribution of your graded exam. Please return my graded exam during class or via the class holding bin. Signed:______________________ ID: ______________________
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Biological Sciences 101 Name_________________________ Dr Neil Hunter Fall Quarter 2005 ID___________________________ FORM A Final Exam Question Points 1 ______ 2 ______ 3 ______ 4 ______ 5 ______ 6 ______ 7 ______ 8 ______ Grading credit ___ 4 __ Signature and ID# ___ 1 __ TOTAL ______/200
Background image of page 2
Question A1, B2, C2 . (24 pts) a. Name three modifications of eukaryotic mRNAs. (2 pts each) 1. Capping 2. Splicing 3. Polyadenylation b. Name two processes that are involved in altering chromatin structure at eukaryotic gene promoters. (please be specific; 3 pts each ). 1. histone modification/acetylation/methylation/phosphorylation 2. chromatin remodeling by SWI/SNF Transcription factor binding also OK. Give partial credit where appropriate. c. Describe the nature of X-inactivation (no more than two sentences; 6 pts ). X-inactivation is the transcriptional silencing of one of the two X chromosomes in female cells and is established early in development when an entire X becomes heterochromatic, forming a condensed structure called a Barr Body. The same inactive X-chromosome is inherited by all descendents of the cell in which the X chromosome was originally inactivated. Key words underlined (1 pts each) Give partial credit wherever you feel appropriate. d. Why doesn’t X-inactivation cause females to suffer X-linked diseases at the same frequency as males? (no more than two sentences; 6 pts ). X-inactivation occurs randomly in a cell autonomous fashion so that the final female individual is comprised a mosaic of cells with paternally silenced or maternally silenced X chromosomes. In a female who is heterozygous for an X- linked allele, some cells will have the wild-type allele silenced (effectively homozygous mutants) whereas others will have the mutant allele silenced and so the individual escapes the disease. Key points underlined; 2 pts each. Partial credit for anything close at your discretion.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Question A2, B3, C3 . (23 pts) Seven cosmid clones from a genomic library were RFLP mapped by digestion with Sau 3A. The panel below represents the gel resulting from this experiment. a. Please write out the order the clones.
Background image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/10/2010 for the course BIO NPB taught by Professor Furlow during the Spring '10 term at UC Davis.

Page1 / 13

NHFinalABCkey'05 - Biological Sciences 101 Dr Neil Hunter...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online