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Lecture_3_NOTES - Lecture3 OnlineHandouts Lec3Notes...

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Lecture 3 Online Handouts: Lec 3 Notes Announcements: Professor office hours for the rest of the quarter: MWRF 4 5 2064 SLB T 4 5 197 Briggs Reading (Recommended): Reading: Ch 3 & 4 Membrane Potential The Neuron Action Potential Membrane Potential
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Membrane Potential Plasma membrane of all living cells has a membrane potential (polarized electrically) Separation of opposite charges across plasma membrane Due to differences in concentration and permeability of key ions Unequal Distribution of Ions Fig. 3 20, pg. 77
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Membrane Potential Resting membrane potential Constant membrane potential present in cells of nonexcitable tisues and those of excitable tissues when they are at rest Nerve and muscle cells Excitable cells Have ability to produce rapid, transient changes in their membrane potential when excited Suppose a concentration gradient exists for K + and A Let’s make the plasma membrane IMPERMEABLE to A K + flows out of the cell Fig. 3 21, pg. 79
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The Equilibrium Potential for K + A concentration gradient pushes K + out of the cell An electrical gradient pulls K + back into the cell Forces balance at equilibrium Electrochemical Equilibrium E i (e.g., E K+ ) Nernst Potential (pg. 79)
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