10-29-09 - Infectious Diseases picture Prof. Ricki...

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Unformatted text preview: Infectious Diseases picture Prof. Ricki Bialstock AHS 151 Pathogen Any virus, microorganism or other substance causing disease Virulence The relative ability of a pathogen to cause disease. How strong the pathogen is Infection Invasion of the body with organisms that have the potential to cause disease Medical Intervention Before 1950- limited interventions available for infection 1950-1980 decreased mortality from infection. In the US, elimination of typhus, cholera, malaria, yellow fever and others Organized vaccination efforts everyone had to get vaccines; like for polio, tetanus, etc 1970s- new infection appear (AIDS ) 1980s- increase in multidrug-resistant organisms bacteria become resistant to to many medications (antibiotics) and its harder to treat the infections and it becomes more contagious Defense Against Pathogens Immune System- 3 Lines of defense Skin/mucosa (physical barrier) skin is a barrier to infects; Ex: if get E. coli on hands, you wont get an infection, but if you then have a cut or put it in your mouth, you will get sick; Prevention wash hands Inflammatory process heat from inflammation helps kill the bacteria Immune system response inflammatory cells fight infection Types of Infection Bacteria Unicellular prokaryotic(without nucleus) microorganism Classified according to shape Cocci round Bacilli rod-shaped Spirochete spiral-shaped Bacterial Classification Shape Response to staining (gram + or -, acid fast) Motility how they move Encapsulation Need for oxygen aerobic (use oxygen) or anaerobic ( dont use oxygen) Types of Infection Virus A pathogen made of nucleic acid inside a protein shell Can only grow or reproduce after infecting a host cell cant grow on their own; need a host Over 400 viruses affect humans Not susceptible to antibiotics cant be treated with antibiotics need antiviral medication Ex: flu virus Types of Infection Mycoplasma A type of bacteria that lacks a cell wall, causes mycoplasma pneumonia See this infection in AIDS patients when the immune system is diminished ( not working well) Types of Infection Rickettsiae Type of bacteria carried by insects such as ticks or fleas Must be in living cells to reproduce Cause Typhus and Rocky Mountain Spotted Fever Types of Infection Chlamydiae Smaller than bacteria but larger than virus Need host cells to live Contain DNA and RNA Respond well to antibiotics Ex: vagina infections Type of Infection Fungus A group of organisms that includes yeast, mold and mushrooms, called mycoses Causes athletes foot , ringworm and yeast infections Types of Infection Protozoa One-celled animal-like organism Causes malaria Ex- roundworms, flatworms Types of Infection Prions...
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10-29-09 - Infectious Diseases picture Prof. Ricki...

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