10-20-09 - Disturbances of Blood Flow and Body Fluids See...

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Unformatted text preview: Disturbances of Blood Flow and Body Fluids See picture Blood Coagulation Normal clotting There are numerous steps in the clotting process Sequential activation of enzymes generates thrombin Thrombin converts the plasma protein fibrinogen to fibrin Fibrin forms the framework of the clot Clotting Pathway picture Disorders of Clotting Failure to clot wont be able to clot; will keep bleeding Examples of causes Hemophilia Decreased platelet count Decreased vitamin K Decreased plasma protein levels Need to stretch slowly Hemarthrosis blood gets inside of joint; if blood is left in joint, it burns the inside of the joint and can cause arthritis Disorders of Clotting Increased tendency to clot Risk factors (examples) Slow blood flow (stasis) Prolonged bed rest or air travel staying in one place for an extended period of time Atherosclerosis hardening of the arteries from high cholesterol Post operative patients Oral contraceptives Estrogen replacement therapy Paralysis Pregnancy Smoking Obesity Terminology Thrombus (thrombosis) a blood clot that forms inside a blood vessel or the heart Embolus (embolism)- anything abnormal traveling through the circulatory system Examples: blood clot, air (subjected to abnormal atmospheric pressures like in an airplane or scuba diving), fat, - in yellow bone marrow; if rum over with a crushing fracture of bone, marrow can get in circulatory system foreign body, tumor cell, bacteria Medical Implications of Thrombus and Embolus May cause: Cerebrovascular accident (CVA) - stroke Heart attack (myocardial infarction) Symptoms include chest pain, shortness of breath, angina (pain in the chest); can have...
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This note was uploaded on 02/11/2010 for the course AHS 151 taught by Professor Bialstok during the Fall '09 term at Nassau CC.

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10-20-09 - Disturbances of Blood Flow and Body Fluids See...

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