Week 5 extras for test

Week 5 extras for test - Aspirin Action In order to undergo...

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Aspirin  Action 
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In order to undergo a release reaction, the  production of prostaglandins by platelets is  required  Aspirin inhibits the conversion of  arachidonic acid into prostaglandins  so  the release reaction does not occur and there  is no platelet plug formation 
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von Willebrand Factor 
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Factor VIII (8)  2 different genetic diseases may be seen with  defects in factor VIII  Hemophilia A  - defect prevents factor VIII  from taking part in the intrinsic pathway  von Willebrand's Disease  - defect prevents  platelets from sticking to collagen, so you can  not form the platelet plug 
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Anticoagulants 
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Prevent clotting  Citrate/EDTA  Heparin  Coumarin 
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Anticoagulants  Citrate/EDTA 
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Chelates (binds) calcium  Therefore, less Ca ++  are available for clotting 
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Anticoagulants  Heparin 
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Activates a plasma protein called  antithrombin III
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Week 5 extras for test - Aspirin Action In order to undergo...

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