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Week 4 - Blood Clotting

Week 4 - Blood Clotting - Blood Clotting Coagulation...

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Blood Clotting 
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Coagulation Hemostasis  Stop bleeding  Reduce risk of hemorrhaging  When bleeding, most likely from capillaries 
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Bleeding 
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Arteries are located the deepest in, so  hardest to get to; then veins; Then capillaries  Capillaries are most superficial 
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Hemostasis 
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3 Phases  Vascular phase  Platelet plug phase  Coagulation Phase 
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Vascular Phase 
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Local contraction of the vessel  Vascular spasm causes a decrease in the  diameter of the vessel Starts in first few seconds of vessel injury  Lasts about 30 minutes 
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Platelet Phase  Overview
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Attachment of platelets to endothelium  Platelets then stick to each other and form a  platelet plug  Prostacyclin inhibits platelet aggregation so  that the platelet plug doesn't get out of control 
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Platelet Phase 
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