13_Memory_III_6 - psychosis No sensory or motor deficits...

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9/25/2008 1 Psychology 2: Introduction to Psychology Day 13 topics Anterograde amnesia Korsakoff’s syndrome Alzheimer’s disease Some causes of anterograde amnesia? Profound anterograde amnesia Chronic thiamine (B12) deficiency (6 weeks) - Causes of this deficiency? Korsakoff’s Syndrome Korsakoff’s Syndrome Damage to the mamillary bodies Alzheimer’s disease Cognitive deficits profound memory loss (anterograde/retrograde) Language: anomic, empty, circumlocutory visuospatial disturbance Behavioral deficits no significant early changes in personality unawareness or denial of illness
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Unformatted text preview: psychosis No sensory or motor deficits 9/25/2008 2 Cortical atrophy Normal brain Cortical atrophy Cortical atrophy - MRI scan Alzheimers disease Normal Alzheimers 9/25/2008 3 Neurofibrillary tangles Amyloid plaques Pathology of Alzheimers disease Degeneration of the basal forebrain cholinergic system Pathology of Alzheimers disease Treatments Cholinergic replacement (Acetylcholine agonist) Compensate for Ach reduction in brain Anti-amyloid agent Try to get rid of amyloid plaques in brain...
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13_Memory_III_6 - psychosis No sensory or motor deficits...

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