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Unformatted text preview: – psychosis No sensory or motor deficits 9/25/2008 2 Cortical atrophy Normal brain Cortical atrophy Cortical atrophy - MRI scan Alzheimer’s disease Normal Alzheimer’s 9/25/2008 3 Neurofibrillary tangles Amyloid plaques Pathology of Alzheimer’s disease Degeneration of the basal forebrain cholinergic system Pathology of Alzheimer’s disease Treatments Cholinergic replacement (Acetylcholine agonist) – Compensate for Ach reduction in brain Anti-amyloid agent – Try to get rid of amyloid plaques in brain...
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- Spring '04
- Psychology, basal forebrain