test 3 2006 - 1 Test #3 IPPH 362 10/25/06 Name_ Seat _ I....

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1 Test #3 IPPH 362 Name_______________ 10/25/06 Seat ________________ I. Short answers. Each answer is worth 2 points. No partial credit. ________ 1 . Direct input of drug to the site of action can allow the use of a lower dose to achieve a clinical effect and can minimize side effects. (true or false) ________ 2. Drugs administered topically as patches undergo hepatic first pass metabolism. (true or false) ________ 3. Interarterial administration of drugs is preferred over intravenous administration because the drug gets to the target organ faster. ________ 4. Drugs with extensive hepatic first pass metabolism exhibit large interpatient variability in blood levels when administered orally. (true or false) 5. Matching 1. benzalkonium chloride 2. benzyl alcohol 3. chlorobutanol 4. ethanol 5. methyl p-hydroxybenzoate 6. propyl p-hydroxybenzoate 7. sorbic acid ________ A. ideal properties for use as a preservative in injectable solutions. ________ B. ideal properties for use as a preservative in ophthalmic solutions. ________ C. only effective as a preservative when in the un-ionized form.
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2 6. Matching 1. chemical instability 2. physical instability 3. therapeutic instability 4. toxicological instability ________ A. epianhydrotetracycline ________ B. mottled tablets ________ C. reduced rate of dissolution. 7. Matching
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This note was uploaded on 02/12/2010 for the course IPPH 362 taught by Professor Hem during the Spring '08 term at Purdue University-West Lafayette.

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test 3 2006 - 1 Test #3 IPPH 362 10/25/06 Name_ Seat _ I....

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