Test 5 2007 cover - 1 Test#5 IPPH 362 Name Seat Solubility in water 500,000 U/mL 100 U/mL potassium penicillin G benzathine penicillin G Density

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1 Test #5 IPPH 362 12/11/07 Name______________________ Seat____________________ Solubility in water potassium penicillin G 500,000 U/mL benzathine penicillin G 100 U/mL Density phenytoin 1.3 v = d 2 ( ρ s - ρ l ) 980 18( η ) Degree of flocculation= sediment volume of test suspense sediment volume of control suspension I. Short Answers. Each answer is worth 2 points. No partial credit. ______ 1. Ophthalmic solutions and suspensions must be sterile but ophthalmic ointments do not need to be sterile. (true, false) ______ 2. If an excessive volume of an ophthalmic solution is applied to the eye as eye drops, some of the solution will enter the Canal of Schlemm and be absorbed systemically. (true, false) ______ 3. A wax in an ophthalmic ointment formulation is desirable as it will thicken the petrolatum and cause the ointment to be retained on the surface of the eye for a longer time. (true, false) ______ 4. Drugs to treat glaucoma must be lipid soluble enough to pass through the cornea. (true, false) ______ 5. Drugs to treat “pink eye” must be lipid soluble enough to pass through the cornea. (true, false) ______ 6. The viscosity of a Newtonian liquid is independent of the applied shear stress. (true, false)
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2 ______ 7. A suspension designed by the structured vehicle approach exhibits thixotropy. (true, false) ______ 8. Suspensions in mineral oil are useful for producing sustained blood levels following intramuscular administration. (true, false) ______ 9. The shear stress produced by shaking a flocculated suspension is greater than the flocculation forces. (true, false)
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This note was uploaded on 02/12/2010 for the course IPPH 362 taught by Professor Hem during the Spring '08 term at Purdue University-West Lafayette.

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Test 5 2007 cover - 1 Test#5 IPPH 362 Name Seat Solubility in water 500,000 U/mL 100 U/mL potassium penicillin G benzathine penicillin G Density

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