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9-17-07 311C F07 L8OL - 86-89 chapter 5 Proteins...

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86-89 chapter 5
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Proteins Proteios (Greek) = first place Most structurally and functionally diverse class of macromolecules Built from amino acid (monomers)
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Overview of Protein Function
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Enzymes Substrate (sucrose) Enzyme (sucrase) Glucose OH H O H 2 O Fructose 2
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Amino Acids Monomers of proteins Organic molecules possessing both a carboxyl group and amino group
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Amino Acid: Structure N C C O OH H H R H α carbon Carboxyl group Amino group
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Amino Acids 20 different amino acids that cells use to build their proteins Differ only in their R group Differ in their properties due to differing R groups
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Amino Acids Categorize amino acids based on properties of side chains (R groups) Polar & Uncharged Polar & Charged Nonpolar
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Polypeptides vs. Proteins Polypeptide Polymers of amino acids Protein One or more polypeptides folded and coiled into a specific functional conformation
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Peptide Bonds Covalent bond that joins amino acids
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Peptide bond formation DESMOSOMES DESMOSOMES DESMOSOMES OH CH 2 C N H C H O H OH OH Peptide bond OH OH OH H H H H H H H H H H H H N N N N N SH SH O O O O O H 2 O CH 2
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