2009 Food Allergies & Sensitivities

2009 Food Allergies & Sensitivities -...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
(CBS, Nov 2005) A 15-year-old girl from Canada died last week after kissing her boyfriend. He had eaten a peanut butter sandwich nine hours earlier and she was allergic to peanuts. Having an allergic reaction from kissing is actually not uncommon, The Early Show medical correspondent Dr. Emily Senay explains. A study of nut allergies a few years ago found about 5 percent of people in the study had an allergic reaction through kissing.” … A Kiss Of Death…Really? “A Canadian coroner confirmed Thursday that a teenager — once believed to have died from a peanut allergy after kissing her boyfriend — died from an asthma attack. A recent study shows at the end of an hour, there is no allergen left in the saliva. . ..She had spent hours at a party with smokers when her breathing problems began.” May 2006:
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
J. Nutr. 135: 2379-2382
Background image of page 2
Food Sensitivities
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Food Sensitivities: Allergies and Intolerances * Reaction that is distinctive and peculiar to an individual * (lactose intolerance)
Background image of page 4
Prevalence of Food Sensitivity in the U. S. Self-diagnosis (questionnaire) data: 5 - 33% of adult population self-report being adversely affected by one or more foods Most cases of food sensitivities are not allergic reactions (i.e. are not true food allergies)   e.g.  Lactose intolerance  :        Deficiency of lactase ( β -galactosidase) enzyme lactose (milk) galactose + glucose               Most common food sensitivity Lactose is not absorbed, fermented by bacterial in lower GI tract Causes intestinal bloating, cramping, diarrhea       Some individuals can tolerate small amounts of lactose lactose
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Lactose intolerance (con’t) Congenital lactose intolerance Rare genetic (inherited) disorder Mutation in the enzyme (gene) per se non-functional enzyme Adult-onset lactose intolerance: Most common cause of lactose intolerance Disappearance of lactase activity with age Down-regulation of lactase gene expression after age 5 Apparent original (ancestral) condition Adult lactase persistence ( lactose tolerance ): DNA mutations upstream of the lactase gene C T Arose 5 - 8,000 years ago in N. Europe (and perhaps elsewhere)
Background image of page 6
T T C T Lactase persistence (mutant) Caucasians: 60-90% Lactase non-persistence (intolerance) Most common world- wide Africans, Asians: 80 – 100% lactase gene Genetic basis of adult lactase persistence (lactose tolerance) chromosome 2 C C Two alleles Ancestral: If:
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Avoidance of lactose Low-lactose milk (immobilized enzyme-treated milk) using bacterially-derived β -galactosidase Enzyme supplements (self-administered β -gal tablets) Treatment of lactose intolerance
Background image of page 8
Food Sensitivities: Allergies and Intolerances (lactose intolerance)
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/16/2010 for the course NS 3450 at Cornell University (Engineering School).

Page1 / 36

2009 Food Allergies & Sensitivities -...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online