Lecture _2 - Jan. 22

Lecture _2 - Jan. 22 - Some aspects of virus history...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Some aspects of virus history leading to modern virology. By Andy Jackson Plant & Microbial Biology READING ON B-space: Chapter 1: A selective history on the nature of viruses; Norkin, Virology: Molecular Biology & Pathogenesis Viruses can cause a multitude of illnesses flower breaking Measles in a Child African Swine Fever Small Pox infection Bird Flu Many plagues thought to be smallpox were recorded from 2000 to 3000 years ago. Smallpox was probably widespread in India by the 5th century B.C. Hippocrates (Father of Greek Medicine) concluded that plagues were caused by small animals in the air that were too small to see. The Greeks and Romans were well aware of rabies and had laws requiring con¡nement of rabid dogs. Plant virus diseases were not recognized in ancient times because the symptoms are usually subtle compared to diseases caused by fungi and bacteria. Ramses V The mummi¡ed head of Ramses V who died in 1157 BC (3160 years ago) showed pustular eruptions. He probably was a smallpox victim!! Virus Diseases clearly impacted Ancient Civilizations The frst written record oF a virus inFection consists oF a stone tablet drawn in ~ 3700 BC in Memphis, the capital oF ancient Egypt,. This heiroglyph depicts a priest called Ruma with clear polio symptoms. The 7th king “Siptah” in the 19th dynasty also died in 1192 BC at about 20 years oF age. His mummy has a withered leg with typical signs oF paralytic poliomyelitis. These fndings suggest that polio was widespread in early Egypt. Polio in early Egypt???? Rabies was one of the Most Feared Ancient Diseases Mesopotamian laws concerning rabid dogs date from 1000 BC. People who let rabid dogs run free were ¡ned. Rabies is present in all continents. Recent epidemics have occurred in North America, Europe & India. Rabies virus causes disease in most mammals. Almost all animals that get rabies die. Transmitted in nature by foxes, raccoons, skunks and bats to domestic animals including dogs. Dogs and bats transmit to humans. First Known Plant Virus Description Earliest known record of a probable plant virus disease was a poem written in 752 A.D. by the Japanese Empress Koken. In this village It looks as if frosting continuously For, the plant I saw In the ¡eld of summer The color of the leaves were yellow Attributed by Saunders, Bedford, Yahara and Stanley to the geminivirus Eupatorium Yellow Vein Virus and its β DNA Satellite Component. Nature 422:831 (2003). EpYVV β DNA Sat Tulipomania & the Stock Market in the 1600’s Tulips with fower breaking symptoms were prized in Europe and Turkey where they sold For very large sums oF money. Tulip bulbs were traded in the market very actively in the 1630’s....
View Full Document

This note was uploaded on 02/16/2010 for the course MCB C 58381 taught by Professor Professorbrittglaunsinger,professorandyjackson during the Spring '10 term at Berkeley.

Page1 / 36

Lecture _2 - Jan. 22 - Some aspects of virus history...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online