Lecture4 - 1 MCB 141 Developmental Biology Lecture #4 Jan....

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Unformatted text preview: 1 MCB 141 Developmental Biology Lecture #4 Jan. 28, 2010 2 Wild-type Ventralized (cactus mutant) 3 Wildtype Laid by cac-/cac- mothers Wild-type Dorsalized (dorsal mutant) Dorsal protein only enters nucleus in cells on ventral side Mother puts dorsal mRNA in the egg uniformly. The dorsal mRNA is translated into protein everywhere, but dorsal protein stays in the cytoplasm dorsally, and enters the nucleus only on the ventral side 4 Dorsalized Ventralized Dorsal protein only enters nucleus in cells on ventral side Mother puts dorsal mRNA in the egg uniformly. The dorsal mRNA is translated into protein everywhere, but dorsal protein stays in the cytoplasm dorsally, and enters the nucleus only on the ventral side 5 6 Oocyte nucleus migrates to future anterior dorsal Makes gurken mRNA which stays localized 2. Gurken protein received by Torpedo receptor on follicle cells 3. Torpedo signal inhibits synthesis of Pipe protein....
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Lecture4 - 1 MCB 141 Developmental Biology Lecture #4 Jan....

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