Lecture06 - MCB 141 A/P axis establish by having gurken...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
1 MCB 141 MCB 141 Lecture #6 Feb. 4, 2010 A/P axis establish by having gurken signal to posterior, polarizing microtubules along the A/P axis D/V axis establish by oocyte nucleus moving to one side, this side becomes dorsal as this is the that gets gurken signal and inhibits pipe synthesis Maternal mRNAs moved into the oocyte from the nurse cells. Some are localized, others are uniformly distribuited in the oocyte
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 D/V enzymatic cascade Nurse cells finish dumping their contents into the oocyte. Oocyte undergoes meiosis just before fertilization. Fertilization occurs just as the egg exits. Bicoid and nanos translation begins D/V enzyme cascade continues Maternal hunchback and caudal translation begins D/V enzyme cascade continues
Background image of page 2
3 Zygotic gap gene (inc. zygotic hunchback) transcription begins Cleaved spatzle binds Toll, dorsal moves to nucleus (Ventral side) Pair-rule gene transcription begins Dorsal pattern well established Segment polarity gene transcription begins Dorsal activates targets
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 18

Lecture06 - MCB 141 A/P axis establish by having gurken...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online