2ALecture 14

A site ready next aa trna elongation elongation nh3

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Unformatted text preview: gation •  Elongation NH3+ HO R1 O CH C NH R2 O CH C O R2 O HO R1 O NH3+ CH C NH CH C O U AC U AC G GG G A A G AU G C C C G C G U U C U A G A A U C G GG G A A G AU G C C C G C G U U C U A G A A U C Ribosome translocates along the mRNA The tRNA remains bound to its codon •  Elongation •  Elongation NH3+ HO R1 O CH C NH R2 O CH C O R2 O R1 O NH3+ CH C NH CH C O R3 O NH3+ CH C O Peptidyl tRNA U AC = tRNA+ growing peptide A G G G C GC G A A G AU G C C C G C G U U C U A G A A U C G GG G A A G AU G C C C G C G U U C U A G A A U C Peptidyl tRNA in the P site. A site ready <-- next aa-tRNA. •  Elongation •  Elongation NH3+ R1 O NH3+ R1 O CH C NH R2 O CH C O R3 O NH3+ CH C O HO R3 O R2 O CH C NH CH C NH CH C O newest a. acid G G G C GC G A A G AU G C C C G C G U U C U A G A A U C G G G C GC G A A G AU G C C C G C G U U C U A G A A U C New peptide bond formed Peptide one a. a. longer 6 2/9/10 •  Elongation NH3+ R1 O CH C NH R2 O CH C NH R3 O HO CH C O •  Termination NH3+ R1 O CH C NH R2 O CH C NH R3 O CH C NH R4 O CH C O A G G G C GC G A A G AU G C C C G C G U U C U A G A A U C A AG G A A G A U G C C C GC G U UC U A G A A U C Now repeat Empty A site: next aa-tRNA? •  Termination NH3+ R1 O CH C NH R2 O CH C NH R3 O CH C NH R4 O CH C O •  Termination NH3+ R1 O CH C NH R2 O CH C NH R3 O CH C NH R4 O CH C O A AG G A A G A U G C C C GC G U UC U A G A A U C A AG G A A G A U G C C C GC G U...
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This note was uploaded on 02/16/2010 for the course BIS 34957 taught by Professor Britt during the Spring '10 term at UC Davis.

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