Exam2s06 - CH 369 Spring 2006 Exam 2 Multiple Choice 1 Which among the following is a ligand of iron in the heme of myoglobin a Porphyrin b Vinyl

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CH 369 Spring 2006 Exam 2 Multiple Choice 1) Which among the following is a ligand of iron in the heme of myoglobin? a) Porphyrin b) Vinyl group c) His F8 d) Propionate group e) His E7 2) Which of the following statements about hemoglobin is FALSE? a) Hemoglobin is a heterotetramer b) Hemoglobin has a higher affinity for O 2 than myoglobin c) Hemoglobin exhibits cooperativity d) All of the above e) None of the above 3) What is the effect of an increase in pH on the O 2 binding affinity of hemoglobin? a) Decreased affinity b) No effect c) Increased affinity d) First decrease and then increase of affinity e) None of the above 4) Which among the following statements about BPG is FALSE? a) BPG stabilizes deoxyhemoglobin b) BPG decreases O 2 affinity of hemoglobin c) BPG binds the heme group of hemoglobin d) BPG is negatively charged e) None of the above 5) Which amino acid can participate in acid-base catalysis? a) His b) Lys c) Cys d) Tyr e) All of the above
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6) Given that the Michaelis Menten Equation is calculate the reaction velocity of an enzyme catalysed reaction when [S] = K M. (Vmax = 10 nM/s) a) 5 nM/s b) 10nM/s c) 0 nM/s d) 20nM/s e) None of the above 7) Which of the following statements about competitive inhibitors is FALSE? a) They bind the active site b) K M is decreased c) V max is unaffected d) Inhibition cannot be overcome with excess substrate e) None of the above Either answer was accepted. 8) Which of the following proteins is associated with transporting cargo? a) actin b) tubulin c) myosin d) keratin e) kinesin 9) Tubulin subunits have a ___________ nucleotide-binding site. a) adenine b) cytosine c) guanine d) thymine e) uracil 10) Microfilaments are made up of polymers formed by a) a single chain of myosin b) a double chain of myosin c) a single chain of actin d) a double chain of actin e) none of the above
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11) During microfilament assembly, monomer subunits are added where in the growing polymer? a) (+) end to lengthen the polymer b) (-) end to lengthen the polymer c) along the outside of the axis to widen the polymer d) both (+) and (-) ends e) all of these 12) All enzymes function specifically by f) altering the free energy of the products g) lowering energy of activation h) chemically changing the transition state species i) increasing the transition state lifetime j) None of these 13) Which of the following amino acids is not a part of the catalytic triad of chymotrypsin? a) His b) Glu c) Asp d) Ser e) None of these are part of the triad 14) Induced fit refers to the concept that enzymes a) place substrates within close proximity to one another b) undergo a conformational change upon substrate binding c) align substrates in the correct orientation d) desolvate substrates before catalysis occurs e) None of these 15) Which of the following statements about hemoglobin and myoglobin is true? a)
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This note was uploaded on 02/16/2010 for the course CH 369 taught by Professor Kbrowning during the Spring '07 term at University of Texas at Austin.

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Exam2s06 - CH 369 Spring 2006 Exam 2 Multiple Choice 1 Which among the following is a ligand of iron in the heme of myoglobin a Porphyrin b Vinyl

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