IGA9e_ch04_labels - 060607

IGA9e_ch04_labels - 060607 - Figure 4-11 Double...

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CHAPTER 4 Mapping Eukaryote Chromosomes by Recombination Copyright 2008 © W H Freeman and Company
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Chapter 4 Opener A recombination-based map of one of the chromosomes of Drosophila
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CHAPTER OUTLINE 4.1 Diagnostics of linkage 4.2 Mapping by recombinant frequency 4.3 Mapping with molecular markers 4.4 Centromere mapping with linear tetrads 4.5 Using the chi-square test for testing linkage analysis 4.6 Using Lod scores to assess linkage in human pedigrees 4.7 Accounting for unseen multiple crossovers 4.8 Using recombination-based maps in conjunction with physical maps
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Diagnostics of linkage
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Figure 4-2 Linked alleles tend to be inherited together
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Figure 4-3 Crossing over produces new allelic combinations
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Figure 4-4 Chiasmata are the sites of crossing over
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Figure 4-5 Crossing over is between chromatids, not chromosomes
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Figure 4-6 Multiple crossovers can include more than two chromatids
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Figure 4-7 Recombinants are produced by crossovers
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Figure 4-8 For linked genes, recombinant frequencies are less than 50 percent
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Figure 4-9 Map distances are generally additive
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Figure 4-10 Longer regions have more crossovers and thus higher recombinant frequencies
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Unformatted text preview: Figure 4-11 Double recombinants arising from two crossovers Figure 4-12 Different gene orders give different double recombinants Figure 4-13c A map of the 12 tomato chromosomes Figure 4-15a An RFLP linked to a mouse disease gene Figure 4-15b An RFLP linked to a mouse disease gene Figure 4-15c An RFLP linked to a mouse disease gene Figure 4-16 Using haplotypes to deduce gene position Figure 4-17 Producing lines for QTL identification and mapping Figure 4-18 Some bands of a DNA fingerprint show linkage Figure 4-19a A microsatellite locus can show linkage to a disease gene Figure 4-19b A microsatellite locus can show linkage to a disease gene Figure 4-20 Phenotypic and molecular markers mapped on human chromosome 1 Figure 4-21 A second-division segregation pattern in a fungal octad Figure 4-22 Four different spindle attachments produce four second-division segregation patterns Figure 4-23 Does this pedigree show linkage? Figure 4-24 Any number of crossovers gives 50 percent recombinants Figure 4-25 Alignment of physical and recombination maps...
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This note was uploaded on 02/17/2010 for the course BIO Genetics taught by Professor Saxena during the Spring '08 term at University of Texas at Austin.

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IGA9e_ch04_labels - 060607 - Figure 4-11 Double...

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