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Ma - BIEN 130 Bioinstrumentation M ”0 I100 Name ”WV £7...

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Unformatted text preview: BIEN 130 Bioinstrumentation M April 29, 2009 ”0 I100 Name: ”WV £7 Score: /20.0 €1,090, H: O ('2wa “’00 a. b. 0. Low pass filter 9 High pass ﬁ[email protected] é Bandpass filtertﬂ Notch filter @ Derive the complex transfer function for this circuit. What is the phase difference between the input and output? /@ ’BV‘M Vovd> «Lt; -( / (M t _/ : ‘_. O .: / HM VM—VA- K “W 4’ l“ & Viv T m!» (a in What type of circuit is this? Mark all that apply. @ lnverting ampliﬁer ‘ m Non-inverting amplifier i4, 6) G3 I Differential ampliﬁer P Va. *5 - v~i - / Voltage divider g-a w‘L < .2._ €ewL>( Disclaimer: This quiz problem is in no way an endorsement of making torture devices. It’s just a little hard to think of a reason to have to connect random parts without making the question even more difﬁcult and involved. Jigsaw wants to make a device that will electrically shook his victim if the victim cannot continually jump up and down at a rate of 1 Hz or greater. He has the following parts: a strain gage, a Wheatstone bridge, a random assortment of op-amps, resistors, and capacitors, and a few Ag/AgCl electrodes. Design a system that will output a large magnitude voltage signal across two electrodes when a person jumps at a rate below 1 Hz. Be as specific as possible regarding any necessary resistances, capacitances, etc. Sketch the layout of any circuits and of the system overall (placement of the person, electrodes, etc). An electronics company wants to design a sleeping aid for patients undergoing long- term EEG monitoring. The system should play soothing music when the patient is awake, and decrease the volume of the music as they fall asleep. The system should send a signal to turn itself off only when the patient enters slow wave sleep. Describe how to design such a system, and be as specific as possible. Mhrue 3% [w {as e {2 He,— .\VA E , I869 ‘ ¢ﬂ Mr» 5.. a; He 69 m @ @ i.» {\$56 @ ”if 69 Tetraethylammonium (TEA) affects nerve function by blocking potassium channels. The most visible effect of TEA is to slow down repolarization of the membrane following an action potential. However, the blockage of potassium ion channels (meaning the permeability of potassium goes to zero: PK=0) has a predictable effect on the resting membrane potential as well. Another relevant fact is that the general excitability of a nerve. like the probability of spontaneous activity, is related to its resting membrane potential. The levels of both excitability and spontaneous activity increase when the resting membrane potential is increased (more positive) and decrease when the potential is decreased (more negative). The following questions pertain to a squid giant axon with a threshold potential of —40 mV, and all normal conditions (below) apply unless otherwise indicated. g=26mV @ T=298K PK :PNa :PC, =1.00:0.04:0.45 at rest PK :PNa :PC, = 1.00 : 20.0 : 0.45 at action potential peak Ion 400mM 50mM 52mM 20mM 440mM 560mM Cytoplasm Extracellular a. Gamma-aminobutyric acid (GABA) is a neurotransmitter that causes an increase in the opening of both potassium and chloride channels. Assume that a sufﬁcient amount of GABA is introduced to increase the permeability of both ion channels by10%. Calculate the rPestin memfbrane potential. ( 7 «(w 0445 52 + ' . Ll 20 +0.0 0 + . ﬂ Walk?” ”‘w‘ ”’71 “1.: 2w LM—J'Tﬁol) Vn‘ F I" KLK'JHKANJH QM]. ( > 1.1(H°0>*0~°*(\$°)*0- 9 _ 24 , M = 26),, ‘5?“ 442.36 mu ‘ " quor 1+1T+l ls GABA an inhibitory or excitatory neurotransmitter? That is, based on the difference between this resting membrane potential and the normal resting membrane potential (with no GABA), is the nerve more or less excitable? (ll/«MM «Lil-a V ALM—‘i-l"t°”“°””“°’”*’s ‘ 5%! Mﬂv a. v I m: - . , . ' 56 3 ,(mg)4o.o‘+(7o7+ o 9.) l 0 ,g“40.\\/ a» .l— *6 (as «21¢;th 3: mum/3 c. Tetrodotoxin (TTX) is a neurotoxin that blocks voltage-gated sodium ion channels. Calculate the membrane potential at the peak of an action potential for a nerve with TTX. What is the significance of this value when it is compared to the threshold potential? . W.z&t%wwta UM 5 Zé L1 '(quo)¥o (50)+ 0'46 (560) 632— a. b. If a normal EKG signal is shown below, sketch the shape of an EKG for a person where one of the ventricles contracts slightly later than the other and at a much slower rate? ‘ A z Outline the operating principle of a digital scale @asQribéed in class. What are the measurand, sensor, signal processing, and output dIsplay? @ “(5me ‘ MAS} [wMS‘i’ @ WW “‘“l‘a Z W Write out the functional form for a measured voltage waveform with the following Fourier transform. ...
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