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#9 PH150A Feb8 Randomized Control Trials

36 httpwwwvirtualcancercentre comuploadsvmcdiseaseima

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Unformatted text preview: detected early. 36 http://www.virtualcancercentre. com/uploads/VMC/DiseaseIma ges/455_Basal_Cell_Carcinom a_of_the_Skin.jpg http://www.nlm.nih.gov/medlineplus/enc y/images/ency/fullsize/2474.jpg Basal Cell Cell Carcinoma Squamous Cell Cell Carcinoma 37 Melanoma Melanoma nus/images/media/medical/hw/h9991258.j pg 38 Melanoma Melanoma In 2005 53 In 2005, 53,792 people in the US diagnosed people in the US diagnosed 8,345 8,345 died Increased significantly by 7.7% per year from Increase i l 2003 to 2005 among men and 2.9% per year from 1993 to 2005 among women 1993 2005 Life Life time risk: 2% (1 in 50) for whites, 0.1% (1 in in 1,000) for blacks, and 0.5% (1 in 200) for Hispanics.http://www.cdc.gov/cancer/skin/statistics/trends.htm, http://health.nytimes.com/health/guides/disease/melanoma/riskhttp://health.nytimes.com/health/guides/disease/melanoma/risk-factors.html 39 Melanoma Risk Factors Melanoma Risk Factors UV UV light exposure Moles Moles Light skin and eye color Li Personal Personal or family history http://t3.gstatic.com/images?q=tbn:cbzt8MdbvWmmM:http://ehp.niehs.nih.gov/docs/2006/114Males Males 7/tanning.jpg Increases Increases with age, but most common cancer <30 years Xeroderma pigmentosum (defect in an enzyme that Xeroderma pigmentosum (defect in an enzyme that normally normally repairs damage to DNA) Immune suppression Immune suppression http://www.cancer.org/docroot/LRN/LRN_0.asp?dt=39 http://www.cancer.org/docroot/LRN/LRN_0.asp?dt=39 ; https://www.csmc.edu/5339.html 40 Text-Message Reminders to Improve Sunscreen Use: A Randomized Controlled Trial using Electronic Monitoring Armstrong A, et al, Arch Dermatol 145: 1230-1236, 2009 Objective: To evaluate effectiveness of cell phone text messages to improve adherence to sunscreen application Participants: 70 volunteers, 18+ years with cell 70 volunteers 18+ years with cell phone and texting ability from the general community Intervention: ½ got messages for 6 weeks, half did not. Outcome: number of days applied sunscreen for 6 weeks 41 Flow diagram of participant progress through the randomized trial Armstrong, A. W. et al. Arch Dermatol 2009;145:1230-1236. Copyright restrictions may apply. 42 43 Instructions for Study Participants Armstrong, A. W. et al. Arch Dermatol 2009;145:1230-1236. 2009 Copyright restrictions may apply. 44 Assessing Assessing the Association of the Text Intervention Intervention with Adherence Rates Sunscreen Use Text Message YES NO YES NO a c b d 45 Adherence rates stratified by weather Armstrong, A. W. et al. Arch Dermatol 2009;145:1230-1236. Copyright restrictions may apply. 46...
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