BIO365R test1 Draper spring 2009

BIO365R test1 Draper spring 2009 - BIO365R Spring 2009 Exam...

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Please do not open exam until told to do so. Relax. Write your name at the top of every page. We are looking for very short answers. The day before yesterday, Timmy was 13 years old. Next year he'll be 16. What is his birthday, and what is today's date? December 31st, January 1st. BIO365R Spring 2009 Exam 1 Name_______________________________________ Do not meddle in the affairs of dragons, for you are crunchy and taste good with ketchup. Page 1
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The Ion, the Itch, and the Bathrobe Once upon a time, I bought a bathrobe. It was a nice bathrobe, but it was too scratchy. It made me itch. This was caused by receptors in the _____ sensory _____ neurons that brought information from the ______ peripheral _____ nervous system into the spinal cord. These efferent / afferent / indifferent (circle one) neurons have cell bodies in clusters on either side of the spinal cord called ____ ganglia ______ . When the receptors de- tected the scratchiness of the bathrobe, sodium was allowed to enter the cell. This caused a repolarization / hyperpolarization / depolarization (circle one) of the cell ʼ s membrane potential. Since I can feel the scratchiness of the bathrobe, this change must have reached __ threshold _____ and this opened the ___ activation ____ gate of sodium channels resulting in an action potential. This speciFc gate is affected by a poison called __ ß toxin __ found in scorpions. These sodium channels are found in the ___ axon ____ of the neuron, which is wrapped by a kind of glial cells called __ Schwann Cells ___ which provide insulation. This insulation is critical in that it reduces __ capacitance ______ at the same time this is increasing membrane __ resistance ________ . The combination of these effects will speed up the radial / axial / medial (circle one) current. There are gaps in the insulation called: __ Nodes of Ranvier ________ . Once the action potential propagates to the terminus, the membrane potential will open ____ voltage-gated Calcium channels _____ which allow an ion to enter the cytoplasm and bind to ___ synaptotagmin ___ which is a V-snare. This will, in turn affect the snare complex composed of: _____ synaptobrevin _______, ___ Snap-25 _____, and ____ synapsin _____. These will cause the __ vesicle _____ containing neurotransmitter to fuse with the terminal membrane. The neurotransmitter then diffuses across the ___ synapse __ where it will then bind with receptors on an __ interneuron ____ which then will send a signal to the brain and a motor neuron. BIO365R Spring 2009 Exam 1 Name_______________________________________ Do not meddle in the affairs of dragons, for you are crunchy and taste good with ketchup. Page 2
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Calcium 2] Name three proteins bound by calcium: synaptotagmin, calmodulin, voltage-gated calcium channels 3] Name an organelle that stores calcium: endoplasmic reticulum, mitochondria 4] List four proteins that are involved in clearing calcium from the synaptic bouton after it enters the cytoplasm: Na+/Ca++ antiport, H+/Ca++ symport,
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This note was uploaded on 02/21/2010 for the course BIO 45 taught by Professor Sadasivan during the Spring '08 term at University of Texas at Austin.

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BIO365R test1 Draper spring 2009 - BIO365R Spring 2009 Exam...

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