1-22-10BlastulaFormationPhylogenetics

1-22-10BlastulaFormationPhylogenetics - BIOL13100 Biology...

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Unformatted text preview: BIOL13100 Biology II: Development, Structure, and Function of Organisms January 22, 2010 Dr. Nancy Pelaez Lilly G-224 [email protected] Oxytocin @ 3Dchem.com Peptide hormones: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 Oxytocin (OXT) most mammals Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Ile-Gly-NH2 Mesotocin all birds, reptiles, amphibians http://www.3dchem.com/molecules.asp?ID=355# Peptide hormones: Vasopressin Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 http://www.3dchem.com/molecules.asp?ID=356 ?? HOTSEAT What is the difference between oxytocin and vasotocin peptides? Figure 41-8 Atomic and molecular levels: Cellular level: Tissue level: Organ level: System level: Organism level: Membrane protein in nerve cells regulates a flow of ions. Electric signal mediated by ion flows travels down length of neuron. Electric signals travel from cell to cell in nervous tissue. Nervous tissue and connective tissue in brain aid in sight, smell, memory, and thought. Nervous system controls breathing, digestion, movement, and other functions. Systems work together to support life. Model and properties of receptor functions with OT/AVP Receptors as examples at http://www.gpc V1 Receptors are in blood vessels (vasoconstri- ction) and V2 Receptors are in kidneys (for reabsorbing water and concentrating urine) AVP is released by the brain. Responses depend upon the receptor in cell membranes at the tissues. A negative feedback loop can restore blood pressure (for example, with hypovolemia – drop in blood volume – for knifing victims). An important adaptation Published by AAAS Donaldson et al., Science 322, 900 -904 (2008) Oxytocin and vasopressin homologs Slightly different primary sequences can cause very small differences in tertiary structure and Cys residues for the disulfide linkage are conserved across species Figure 32-1-Table 32-1 Sometimes organisms that look quite different at the adult stage show similarities in molecular structures and functions at other stages of development Figure 21-00 Table 21-1 Figure 32-5c Bilateral symmetry Lizard Single plane of symmetry Posterior Anterior Figure 21-5 Anterior (toward head) Right …are initially established in embryos (such as this mouse). The three body axes observed in humans and other animals… Left Posterior (toward “tail”) Ventral (toward belly) Dorsal (toward back) Posterior (toward “tail”) Dorsal (toward back) Left Ventral (toward belly) Right Anterior (toward head) Blastula Formation...
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This note was uploaded on 02/21/2010 for the course BIO 131 taught by Professor Paleaz during the Spring '10 term at Purdue University.

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1-22-10BlastulaFormationPhylogenetics - BIOL13100 Biology...

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