StudentLecture_13%26%2014

StudentLecture_13%26%2014 - Lecture 13 10/8/2009 Reading...

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Unformatted text preview: Lecture 13 10/8/2009 Reading for Lecture 13: Sections 8.6, pp. 367- 375 and Lab, Chapter 5 October Break, no Tuesday lecture next week Lab: Molecular Structure and Geometry, Ch. 5 Homework due Friday. Reading for Lecture 14: Sections 10.1 (pp. 442- 447), 10.2 (pp. 447-450), 10.3 (pp. 461-462, 466- 468), 10.4 (pp. 468-472) Venkatraman Ramakrishnan, Thomas Steitz and Israeli Ada Yonath's work on ribosomes has been fundamental to the scientific understanding of life. Ribosomes are crucial to life because they produce the proteins that control the chemistry of plants, animals and humans. The three laureates used a method called X-ray crystallography to pinpoint the positions of the hundreds of thousands of atoms that make up the ribosome. Their three-dimensional models show how different antibiotics bind to ribosomes an understanding that has helped other researchers develop new drugs to fight bacterial infections. The Nobel Prize in Chemistry, 2009 The Nobel Prize in Chemistry, 2009 "These models are now used by scientists in order to develop new antibiotics, directly assisting the saving of lives and decreasing humanity's suffering," the academy said in its announcement. Ribosomes are complexes of RNA and protein that are found in all cells with nuclei. The ribosome is part of the mechanism that translates a DNA sequence into a protein sequence Many of today's antibiotics cure diseases by blocking the function of bacterial ribosomes, the citation said. "Without functional ribosomes, bacteria cannot survive. This is why ribosomes are such an important target for new antibiotics." Valence Shell Electron Pair Repulsion Theory (VSEPR Theory) VSEPR Theory helps us understand the VSEPR Theory helps us understand the geometry around individual atoms. geometry around individual atoms. Structure with VSEPR Theory helps us Structure with VSEPR Theory helps us recognize incorrect Lewis structures recognize incorrect Lewis structures Most important factor in determining geometry Most important factor in determining geometry is relative repulsion between is relative repulsion between _____________ ______________ . M M olecule adopts the shape that olecule adopts the shape that ___________ the electron pair repulsions. the electron pair repulsions. Structure in Peptides _________________________________________ _________________________________________ or Ideal Electron Unit Geometries Ideal Electron Unit Geometries Electron unit = ____________________________________ ________________________________ VSEPR - Valence Shell Electron Pair Repulsion Theory Each unit of valence electrons around a central atom (single bonds, multiple bonds, and lone pairs) is located ______________ as possible from the others in order to minimize repulsions....
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StudentLecture_13%26%2014 - Lecture 13 10/8/2009 Reading...

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