Lecture Notes 9-8-08 - ThePlasmaMembrane...

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The Plasma Membrane Every cell is contained within a plasma  membrane. This membrane serves as an interface between  the interior components of the cell and the  extracellular space. The plasma membrane is the portion of cell that  will directly interact with the extracellular space  by: Acting as a selective barrier, Connecting with extracellular matrix or other cells, Receptor, G-protein, or ion channel mediated  signaling.
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Membrane Properties The membrane is formed from molecules  (phospholipids) that are amphipathic One part is hydrophobic (water-insoluble) One part is hydrophylic (water-soluble) These molecules spontaneously self- assemble into a closed phospholipid  bilayer.
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Membrane Proteins The plasma membrane is not made up  solely of a phospholipid bilayer.   There are many different types of proteins  that associate with the membrane. Some of these proteins are attached to the  lipids in the bilayer.  In others - the transmembrane proteins -  the polypeptide chain traverses the lipid  bilayer. 
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The portion of the protein within the lipid 
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Lecture Notes 9-8-08 - ThePlasmaMembrane...

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